| Date | Time | Whipple Field 2 | Whipple Field 3 | Whipple Field 4 |
| 10/23/2021 | 9:00 AM | RI Storm vs. RI Rampage | Coventry Crush vs. Wachusett Stars | East Bay Rage vs. EC Scorpions |
| 10/23/2021 | 11:00 AM | Waves vs. RI Storm | EC Scorpions vs. RI Rampage | East Bay Rage vs. Wachusett Stars |
| 10/23/2021 | 1:00 PM | ECS DeMarco vs. SC Rebels | Maine Thunder vs. BNB Rox | WW Warriors vs. Coventry Crush |
| 10/23/2021 | 3:00 PM | SC Rebels vs. NE Impact | Maine Thunder vs. Bay St. Thunder | Waves vs. Worcester Union |
| 10/23/2021 | 5:00 PM | ECS DeMarco vs. BNB Rox | WW Warriors vs. Bay St. Thunder | Worcester Union vs. NE Impact |